Research indicates that reducing NNMT activity with 5-amino-1MQ alters metabolic processes, promotes changes in adipocyte function, and modulates muscle and nerve physiology
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The deficiency can lead to subtle cognitive and neurologic changes, as well as to more severe anemia and dementia
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5Amino1MQ Peptide (NNMTi), full name 5Amino1methylquinolinium chloride, is a highly selective smallmolecule peptide inhibitor targeting NNMT
When B12 is deficient, a buildup of methylmalonic acid occurs, which is toxic to the nervous system and contributes to neuropathy