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Some prescription IBD medications, such as sulfasalazine and methotrexate, may interfere with the absorption of folic acid

Moreover, bromelains capacity to increase apoptosis has been shown in other cancer types

When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives

The animals were kept in a controlled environment with stable temperature and humidity under a 12-hour light/dark cycle

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