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It has been recognized as an important causal precursor during the development process of gout and can significantly increase risk of incident gout, and many individuals suffering from hyperuricemia form MSU crystals and develop gout, however, some of those individuals do not follow the trend, up to 76% of patients with asymptomatic hyperuricemia (AHU) could not detect MSU crystal deposition, and 10% of patients with AHU will not suffer from gout for life [5]

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