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Our results are in line with previous findings showing the direct inhibitory effect of GSH on MMP-2 gelatinolytic capacity, and GSH-mediated increases in MMP-9 gelatinolytic activity in vitro (Bogani et al., We additionally found that GGC can increase intracellular GSH levels and lower the GSSG/GSH ratio in astrocytes

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However, not all studies in humans support an impact of menopause on fatty acid oxidationno significant difference was found in the rate of fatty acid oxidation (assessed by measuring plasma levels of 3-hydroxybutyrate, a byproduct of fatty acid oxidation), between pre- and postmenopausal women matched for abdominal obesity (58)

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one carbon metabolism), and low statistical power