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In vitro and in vivo studies investigated its effects on endothelial cell tube formation, VEGF expression, and collateral vessel development in ischemia models

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1,4 Hyperglycemia, dyslipidemia, and insulin resistance activate various metabolic pathways, resulting in oxidative stress, mitochondrial dysfunction, inflammation, and microvascular damage, culminating in neuronal injury, Schwann cell damage, and myelin sheath degeneration

It was liver efficiency during fat mobilization