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Statins can be used to treat coronary heart disease by alleviating endothelial dysfunction, inhibiting adhesion between leukocytes and endothelial cells, resisting oxidation, stabilizing plaques, affecting blood flow, suppressing smooth muscle cell proliferation and exerting other effects [29, 30]

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In diabetic wounds, hypersecretion of IL-1 promotes degradation of the matrix through activation of matrix metalloproteinases and inhibits the activity of the fibroblast, further delayed the tissue regenerative process

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[DOI] [PubMed] [Google Scholar] 67.Arakawa T., Kita Y., Timasheff S.N

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