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This process avoids adding external molecules since interferon gamma (IFN-) and tumor necrosis factor-alpha (TNF-), two cytokines associated to the SASP, act as natural adjuvant by promoting an immunoreaction

241, 282 Tuovinen, M

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A 2014 paper in the International Journal of Colorectal Disease reported a Phase 2 randomized controlled trial of ipamorelin for the management of postoperative ileus in bowel-resection patients, providing one of the few human-clinical-trial datasets for this class of molecule (PMID 25331030)

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PLoS One 12 (4), e0175499