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Semaglutide (the active ingredient in the brand-name medications Ozempic and Wegovy ,) can start working within one hour to 3 days after you first take it

However, people who go between diarrhea and constipation may notice stool color differences based on how quickly food is moving through the gut at different times

Mizuno et al

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The intervals themselves are free from signs of disease. His observations were later included in the definition of the periodic syndrome of childhood described by Wyllie and Schlesinger in 1933