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Safety / regulatory read-through: Vafseo was approved by the U.S

Some individuals, such as those with MTHFR gene variants, may benefit more from active forms like methylfolate

Moderate and severe TBI carries substantially higher risks of long-term disability, including impaired memory, executive function deficits, emotional dysregulation, and increased vulnerability to neurodegenerative disease later in life

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Patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 should not use this medication

Moschovaki Filippidou F, Kirsch AH, Thelen M, Ketszeri M, Artinger K, Aringer I, et al