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Quick Answer: There is no established evidence that tirzepatide affects multiple sclerosis disease activity, progression, or causes MS-related complications

doi: 10.1002/jnr.22565 69 AlvarezEMartnezMDRonceroIChowenJAGarca-CuarteroBGispertJDet al

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The cytoplasmic fraction was collected by centrifugation at 10,000 g for 10 min

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Although these studies are not about RA directly, they offer hints that GLP-1 drugs might be useful for various inflammatory diseases, RA included