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Strategies to minimize immunogenicity include careful peptide design to maintain similarity to natural sequences, appropriate formulation development, and monitoring for antibody formation during clinical development and post-market surveillance

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Monitoring-guided supplementation is the usual approach, typically beginning with oral supplementation if blood tests indicate suboptimal levels, and escalating to IM injection if oral treatment is insufficient or poorly tolerated

Many companies manufacture different reconstitution solutions, including bacteriostatic water for injection, in the US

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Understanding this relationship helps you and your GP interpret your results with greater clarity