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As acetyl-CoA is a universal breakdown product of metabolic substrates, acetylcarnitine becomes the most abundant acylcarnitine species in tissues and blood, acting as a regulator of cellular substrate utilization
Therefore, obese patients may require dose adjustments, though supporting evidence for this approach is limited [53,54,55]
Finally, while the CARDIAB cohort represents a large, national real-world population, the generalizability of these findings to other healthcare systems or countries should be approached with caution
the active weight-loss comparator rules out dieting as the cause
The AIP diet is an elimination diet intended to help you identify food triggers that cause inflammatory symptoms