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Endogenous PTHrP plays an important role in fracture healing as demonstrated in an PTHrP haplo-insufficiency model where reduced cartilaginous and bony callus formation was noted together with reduced endochondral and osteoblastic bone formation [229]

Rifampicin has also been reported to reduce pruritus and abort cholestatic episodes by activation of the nuclear pregnane X receptor and induction of bile acid sulfation

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While night sweats can be uncomfortable, they are not always a sign of a serious problem

The pathogenicity of Th17 cells in autoimmune diseases