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To maintain ER membrane homeostasis, cells use various sense-and-response regulators that combine sensitivity to membrane physical properties with a signaling module capable of feedback control ( Sorting Out the Golgi Unlike the ER, which is a continuous network with a thin and readily deformable membrane to allow facile insertion of nascent membrane proteins, the Golgi apparatus is a polarized organelle composed of stacked cisternae functionally compartmentalized into cis-, medial-, and trans-Golgi (von Blume and Hausser, 2019)

The Journal of Pathology and Bacteriology

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Established direct modulators of GPX4

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