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[13] Most of these reactions, if they occur, subside as the body adjusts to therapy

Standard protocols often begin with loading doses followed by maintenance injections

Among xenobiotics metabolized by CYP2E1 are acetaldehyde, acetaminophen, acrylamide, aniline, benzene, butanol, carbon tetrachloride, diethylether, dimethyl sulfoxide, ethyl carbamate, ethylene chloride, halothane, glycerol, ethylene glycol, N -nitrosodimethylamine, 4-nitrophenol, pyrazole, pyridine, and vinyl chloride

Targeting oxidative stress in disease: Promise and limitations of antioxidant therapy

One example is a starting dose given three times per week, then adjusting based on lab results and symptoms

PMCID:PMC3353819