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Pharmaceutics (2024) 3

This temporary reaction occurs in approximately 5-10% of users and stems from the body's natural inflammatory response to the injection itself, not an allergy to the medication

Proposed mechanisms include ischemic mucosal injury, mechanical pressure from the coil mass, and chronic inflammation

Evaluation of the Influence of Intermolecular Electron-Nucleus Couplings and Intrinsic Metal Binding Sites on the Measurement of 15 N Longitudinal Paramagnetic Relaxation Enhancements in Proteins by Solid-State NMR

MOAA has challenged this decision, but no reversal is expected in the near term