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It reduces appetite by acting on hunger centers in the brain, slows gastric emptying so you feel full longer, and improves insulin sensitivity, which together support weight loss over time when combined with lifestyle modifications

Data from the STEP trial program shows that patients who discontinue semaglutide commonly regain a substantial portion of the weight they lost, without a specific number we can promise for any individual

Participants also reported vomiting and constipation

Cardiovascular Diabetology, 19(1), 111

The FDA recommends talking with your healthcare provider before considering them

GLP-1 receptor activation slows gastric emptying and alters gut signaling