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In those malignant MCA infarctions, edema generally peaks between 48 and 96 h after the onset, with a fatal outcome in 80% of patients in the first week (76, 82)

Concurrently, T3 upregulates L-type calcium channels while reducing buffering proteins such as calbindin, creating a vulnerability to excitotoxicity (9496)

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A new study warns that while Ozempic, Mounjaro and similar diabetes and weight loss drugs may decrease the risk of most cancers, they may actually increase the odds of developing kidney cancer by more than a third

Several biological pathways are being studied, though they likely do not all contribute equally in clinical practice