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In the following month, the Trump administration publicly announced that it was preparing a ban on flavored e-cigarettes to reverse the concerning epidemic of youth e-cigarette usage

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Both conditions had significant independent effects (OR=4.5 for COPD, OR=2.3 for CAD) and the addition of each in logistic regression models reduced the OR estimates for smoking/vaping and smoking alone compared to the estimates of Table 1

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doi:10.1258/phleb.2007.007027

The carcinogens present in tobacco smoke can cause irreparable damage to cellular DNA, leading to the uncontrolled growth of cancerous cells