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Cardiometabolic Health: Research indicates improvements in systolic blood pressure (up to 8 mmHg reduction), triglycerides, LDL cholesterol, and fasting insulin levels
Joseph Rizzo, the director of neuro-ophthalmology at Mass Eye and Ear in Boston
Oral peptide therapeutics are an area of intense research in several therapeutic areas, and, although some oral peptides are available for certain indications, such as diabetes, there are currently no targeted oral peptides available for the treatment of patients with IMIDs
Amongst people with HF, up to 50% are estimated to have type 2 diabetes and, vice versa, around 20% of the over 500 million people living with type 2 diabetes have been shown to have comorbid HF (ClinicalTrials.gov IDs NCT04916470 and NCT04788511), it may be relevant to consider obesity-related HFpEF as a specific (sub)phenotype, whether coexisting with type 2 diabetes or not
Pregnancy and breastfeeding are handled differently across products, with the weight-management versions generally advised against during pregnancy
