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Romano et al., 2015)

In a 2023 randomized trial published in the ClinicalTrials.gov database, participants experienced an average of 1724% total body weight reduction after 48 weeks of treatment

We propose that the seemingly opposing roles of GSH in cell survival and cell death reflect the spatial, metabolic, and microenvironmental context in which GSH homeostasis is disrupted

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Without that foundation, the effect is very limited