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Dehydration GLP-1 medications can cause gastrointestinal side effects including nausea, vomiting, and diarrhea, especially in the early weeks

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The choice between variants depends on goals: systemic anabolism favors IGF-1 LR3, while targeted local effects or minimizing systemic exposure favors IGF-1 DES

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Liraglutide, 97% sequence identity to native GLP-1, is obtained by derivatizing GLP-1 with a fatty acid (128)