The primary reasons people become deficient usually fall into two categories: Dietary Factors: Since B12 is mainly found in animal products (meat, fish, dairy, eggs), vegans and strict vegetarians are particularly susceptible if they dont consume fortified foods or specific supplements
Dose cycling Some long-term users cycle between doses
In addition, strict avoidance of sun exposure is suggested as well as year round full spectrum sunblock
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Loren Pickart Researcher profile: Google Scholar Loren Pickarts publications are closely connected to the GHK and GHK-Cu literature reviewed in this article, especially discussions of copper peptide biology, skin remodeling, extracellular matrix activity, wound-model research, and gene-expression hypotheses
pH Balance Carefully balanced pH to support stability, safety, and comfortable use