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GLP-1R deletion impairs mitochondrial integrity in astrocytes, and a lack of GLP-1R signaling impairs mitochondrial function and induces a cellular stress response (Timper et al., 2020)

Conclusions This open-label, single-center pilot study suggests that GLP-1-RAs are an effective and safe treatment option for achieving significant weight loss with a favorable effect on headache, leading to reduced acetazolamide dosage in pwIIH

These findings support KT as a promising therapeutic intervention in mildly underweight or weight-normalized AN and warrant testing in a controlled study design, comparing the intervention with, for instance, the Mediterranean diet, which has been tested previously in another population 106

GLP-1 medications are available as both weekly injections and daily pills

Medications help patients recapture that early sense of satiety and control

See a doctor if you notice or experience one of these symptoms