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The TTrials, an RCT focused on testosterone therapy in elderly men with low testosterone, included 788 men aged 65 and above (average age 72) with testosterone deficiency

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Patients on 15 mg lost approximately 6 percentage points more body weight on average than those on 5 mg

Similar results were obtained with erastin-2 or RSL3, two well-known inducers of ferroptosis, while treatment with fer-1 significantly reduced lipid peroxidation, indicating that ferroptosis was implicated in this PA-induced process (Fig

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