PMID 19043625
The most common adverse effects are gastrointestinal nausea, vomiting, diarrhoea and are typically dose-dependent and most pronounced during dose escalation
Additionally, no significant change was observed in human studies, and the results were insufficient to draw any conclusions [28]
It is important to note that DPP-4 inhibitors should not be used in combination with GLP-1 receptor agonists, as both drug classes act on the same incretin pathway and concurrent use is not supported by evidence or current guidance
GLP-1 medications work with your body to make weight loss more manageable by: Reducing hunger and cravings Helping you feel full longer Slowing digestion to improve portion control Supporting steady, sustainable weight loss Instead of relying on willpower alone, these programs help create a natural shift in how your body responds to food
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