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Collectively, this study identifies GGCT as a metabolic switch that diverts Gln flux toward GSH synthesis to maintain redox homeostasis, while enhancing glucose-fueled anaplerosis into the TCA cycle to sustain cell proliferation

Immune cells are highly sensitive to oxidative stress during activation, and the intracellular glutathione pool can influence inflammatory signaling pathways and the balance between pro-oxidant and antioxidant responses

Are there adverse effects of lycopene exposure

Rats were pretreated with icv scopolamine (70 nmol in 2 aCSF) 20 min prior to training followed by the icv infusion of dihexa (0.1 or 1 nmol in 2 aCSF) 5 min prior to daily training

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Thus, the primary cause for the reduction in the pool of Tbr2 + cells appeared to be driven by an IH-dependent increase in cell death among INPs