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Biochim Biophys Acta (2006) 1757(2):11522.10.1016/j.bbabio.2005.11.009 50 ParikhSSanetoRFalkMJAnselmICohenBHHaasRet alA modern approach to the treatment of mitochondrial disease

In a study by Zhang et.al, FeOOH nanoshuttles (NSs) co-loaded with gold (Au) nanodots and an iron-apigenin (Ap) complex were developed to simultaneously induce disulfidptosis and ferroptosis under systemic glucose deprivation [147]

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Therefore, RBCs are more vulnerable to ROS action than other cells of the human body [12]

The idea is supported by maintenance of functional GSH/GSSG levels by Sp in BSO and neurotoxin treated cells as compared to untreated ones which showed a significant decline in the antioxidant ratio probably, due to enhanced formation of glutathionequinones 43

It lead to significant improvements in overall liver health (x)