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Although most patients experience grade 1-2 pneumonitis, it can rapidly escalate to a grade 3-4 irAE with a high mortality rate (50%-60%)

It is a human monoclonal antibody which targets interleukin 1- beta, and a recent abstract looked at its ability to treat and prevent gout attacks, which showed some success.16 As with Rilonacept above, this agent may have a future role in the acute treatment and relatively short-term prevention of gout, and may have a longer-term role in selected patients with problems with multiple other options

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The work of Su et al

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