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They usually occur in the initial phase of starting the treatment or during dose escalation, but improve over time

[2] Pharmacokinetic studies demonstrate rapid systemic distribution with peak plasma levels occurring within 30-60 minutes of intramuscular injection, followed by extensive hepatic storage and enterohepatic recycling

Research suggests semaglutide may have enhanced ability to cross the blood-brain barrier compared to liraglutide, leading to stronger effects on the hypothalamic appetite centers

It is also vital for fetal development and other bodily functions

Inadequate B12 levels can result in anemia, leading to fatigue and weakness

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