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N Engl J Med 384(11):9891002 Davies M, Frch L, Jeppesen OK et al (2021) Semaglutide 24 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial

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Inside target cells, these metabolites bind the B30.2 domain of BTN3A1 and act as a molecular glue that stabilizes BTN3A1BTN2A1 complexes, triggering inside-out activation of the V9V2 TCR [30, 65]

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