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The TRIUMPH-1 study indicates that the 4 mg dose provides a balance between efficacy and tolerability, with lower discontinuation rates due to adverse effects than placebo

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All participants were required to have a baseline A1c of less than 12%, and for basal insulin only users, there was lower A1c limit of 7%

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50 In immune function-related signaling, zinc enhances the development of regulatory T cells, as induced by the transcription factor Foxp3