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A prospective cohort study compared the effect of metformin as monotherapy versus metformin with additional therapy of either insulin or GLP-1 RA on lung function in 32 non-asthmatic patients with T2D over 2 years [99]

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8 GLP1RA GI motility values selected from the literature extended the gastric emptying time to 4 h and mean small intestine transit time to 9 h in the GLP1RA treatment group

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