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Extrarenal clearance of oxalate increases with progression of renal failure in the rat

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In animal models of Alzheimers disease (AD), Parkinsons disease (PD), ischemic stroke, intracerebral hemorrhage (ICH), Huntingtons disease (HD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), depression, epilepsy, and spinal cord injury (SCI), these cellular changes add up to less protein aggregation, less neuron loss, and better functional outcomes

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