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2 Park et al found that oleuropein could selectively inhibit the activity of ER, but had no effect on the activity of ER

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Regarding the expression of core defense molecules, multiple independent research teams have consistently reported significantly downregulated GPX4 protein and mRNA levels in OA patient cartilage tissues, or in vitro chondrocytes treated with inflammatory cytokines like interleukin-1(IL-1) to mimic the OA inflammatory environment, or under direct iron overload conditions

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Scientists conducting research must ensure their experimental protocols comply with research-use regulations