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The results indicated that Liraglutide exhibited the fastest onset, reaching an efficacy plateau (80 % of the E max value) by week 17, whereas Tirzepatide showed the slowest onset, requiring 46 weeks to reach the efficacy plateau

Melatonin attenuates diabetic cardiomyopathy and reduces myocardial vulnerability to ischemia-reperfusion injury by improving mitochondrial quality control: role of SIRT6