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Diabetologia 47 , 15921601 (2004)

They are used for several medical reasons (treating type 2 diabetes, reducing risk of heart-related death in certain patients, and preventing the progression of kidney disease in high-risk patients), but they have gained their fame for their effectiveness as a weight loss drug

[10] Burton JL, Oakley N, Anderson JB

Phase 2 studies in people without diabetes showed double digit weight loss

The absence of MZB-mediated immunity was substantiated by the lack of anti-TNP IgM at 7 days post-immunization with TNP-Ficoll in Gclc fl/fl Mb1-Cre + mice (Supplementary Fig