who does semaglutide not work for Why your weight loss may be optimal with 🤔 Why do some people lose a lot of weight with GLP-1 drugs… while others don't? A new Nature study (~28,000 patients) 7 Reasons You Aren't Losing

You don't do the same thing with blood pressure, "Well, I'll come off my blood pressure meds or cholesterol meds, and see how I do. Some patients may be good candidates for medical therapy alone, particularly those with borderline BMI who have access to medication and do not have conditions such as reflux or a history of pancreatitis, which can be worsened by GLP-1s

Keep a symptom diary to identify specific food triggers

In the pivotal STEP-1 trial , participants receiving once-weekly Semaglutide injections lost an average of 14.9% of their baseline body weight over 68 weeks , compared to just 2.4% in the placebo group

Gastroparesis can change digestion in ways that are easy to miss at first

Anatomy & Pathophysiology The Pancreas and Insulin Regulation: The islets of Langerhans in the pancreatic parenchyma contain beta cells (insulin-secreting), alpha cells (glucagon-secreting), and delta cells (somatostatin-secreting)

Losing weight without resistance training results in proportional loss of fat and muscle