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Clinical Research Progress of GCGR-Targeted Drugs According to incomplete statistics, there are currently 103 drugs targetingGCGR worldwide, but most are either in preclinical stages or have shown no progressAmong the drugs in clinical stages, there are 8 peptide-based drugs, 2 small molecule drugs, and 7 other types, including fusion proteins, monoclonal antibodies, and hormones

IBS presents in several subtypes, often classified using the Bristol Stool Chart: IBS with constipation (IBS-C) : Predominant hard or lumpy stools IBS with diarrhoea (IBS-D) : Predominant loose or watery stools IBS with mixed bowel habits (IBS-M) : Alternating constipation and diarrhoea IBS unclassified (IBS-U) : Insufficient abnormality of stool consistency Common symptoms include bloating, abdominal distension, urgency, and a sensation of incomplete evacuation

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