Whichever medication you are taking, your healthcare provider will likely have you start with a low dose, before slowly increasing your dose over a period of weeks to months until you reach an effective maintenance dose
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The following is a comparison of the incidence rates of gastrointestinal adverse events with semaglutide at different doses from randomized controlled trials: Serious events and warnings: Rare but serious side effects of semaglutide and dulaglutide are: Pancreatitis (inflammation of the pancreas) Changes in vision (worsening diabetic retinopathy) Gallbladder issues (cholecystitis and cholelithiasis) Injection site reactions (redness, inflammation, infection, and scarring) Severe stomachache Suicidal ideation Excessive burping Mood and behaviour changes Hypoglycemia Allergic or hypersensitivity reaction High risk of aspiration (stomach content entering the respiratory tract) during surgical procedures that require anesthesia or sedation GLP-1 medications are contraindicated for patients with a personal or family history of medullary thyroid carcinoma and MEN 2 syndrome (Multiple endocrine neoplasia type 2 syndrome)

To relieve indigestion symptoms, eat smaller portions of foods throughout the day
The FDA has approved semaglutide as a safe way to help with weight management and weight-related conditions
The medication also slows gastric emptying, which means that food, including carbohydrates, moves more slowly from the stomach into the small intestine where absorption occurs