The main differences are their licensed uses and dosing Wegovy is specifically approved for weight loss and reaches a higher maximum dose, while Ozempic is licensed for diabetes management in the UK
Derived from a compound found in Gila monster saliva (exendin-4), it shares approximately 53% homology with human GLP-1, much less than semaglutide at 94%
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The American Diabetes Association (ADA) now recommends GLP-1 agonists for overweight individuals with diabetes, particularly those who experience frequent hypoglycemia with insulin or sulfonylureas
serious risks include pancreatitis and gallbladder disease, and neither is licensed by the MHRA, so use outside clinical trials is not supported
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