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Although the GLP-1R antagonist exendin-9-39 (Ex9) is not used clinically, it has been used for research purposes because it blocks the endogenously released GLP-1

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For each patient, the risk-benefit tradeoff critically depends on a patients clinical characteristics and their preferences and clinicians recommendations, senior study author Rong Xu, PhD, professor and director of the Center for AI in Drug Discovery at Case Western Reserve University, told Healthline