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Secondly, the possible epidemiologic changes over time may have not necessarily coincided with the periods fixed in the study, as has been pointed out before.31 Finally, there may have been an inherent selection bias due to the retrospective nature of the study

Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial

The results of this study were significant for both men and women

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