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Mechanism of Action of IGF-1 LR3 IGF-1 LR3 binds to the IGF-1 receptor (IGF1R) , activating intracellular pathways such as: PI3K/Akt/mTOR pathway Drives protein synthesis and muscle growth MAPK pathway Influences cell proliferation and differentiation Key effects include: Stimulating muscle stem cells (satellite cells) Increasing nitrogen retention in muscle tissue Enhancing glucose uptake for energy and glycogen replenishment Promoting connective tissue healing 6

Reconstituted BPC-157 must be refrigerated at 28C and used within 28 daystemperature excursions denature the peptide structure and eliminate therapeutic activity

2 10 3 cells (PC-3, DU-145, LNCaP, 22Rv1, BPH) were seeded into 96-well plates and treated with ALCAR (range: 50 M, 100 M, 200 M, 500 M, 1 mM, 5 mM or 10 mM) for 24, 48 and 72 h

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