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Figure 2 2.3.2 Neutrophils BAs suppress neutrophil infiltration into inflammatory sites, thereby inhibiting the onset of acute gout

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Once activated, caspase-3 initiates the cleavage of a downstream substrate, such as nuclear poly (ADP-ribose) polymerase (PARP), which facilitates cellular disassembly and serves as a biomarker of cell apoptosis

Address correspondence to: Mansoor Husain, Toronto General Hospital Research Institute, 101 College Street, TMDT Room 3-909, Toronto, Ontario, M5G 1L7, Canada