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In addition to its effect on glucose homeostasis, glucagon has lipolytic and thermogenic actions in liver and adipose tissue which contribute to its weight-lowering effects [20]

For the specific query retatrutide back pain adverse event trial , the important context is that back pain was documented as a lower-frequency adverse event in the published Phase 2 data, separate from gastrointestinal abdominal pain

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Timing Optional Monitoring guidance is GH-secretagogue pathway-based because ipamorelin-specific clinical monitoring standards are limited