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Oxyhemoglobin suffers autoxidation daily (23%), with oxidation of heme ferrous iron into ferric iron [10], leading to the formation of methemoglobin (metHb), which is not capable of O 2 transport, and the release of superoxide anion that is converted to H 2 O 2 , with a lower oxidant capacity [11]

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The cognitive battery was administered by a trained team member in a controlled, quiet environment under standard lighting conditions (defined as well-lit, neutral illumination devoid of harsh shadows or glare)

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