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N Engl J Med 304(26):15681575 McIntosh K (2005) Coronaviruses in the limelight

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[5] The researchers also note that IR and IGF1R act as identical portals to the regulation of gene expression, with differences between insulin and IGF-1 effects due to a modulation of the amplitude of the signal created by the specific ligand-receptor interaction. The IGF-1R is referred to as the physiologic receptor due to its potential higher affinity (approximately 100 times higher) for IGF-1 as compared to the insulin receptor

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Medications that delay stomach emptying may also cause gastroparesis, the American College of Gastroenterology notes

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