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Izumori from Kagawa University in Japan around the 90s, many studies were then conducted in Japan

Its important to understand how IGF-1 LR3 differs from peptides like Ipamorelin/Sermorelin and CJC-1295

In terms of the reduction in levels of free testosterone, 3 studies (with 39 and 41 subjects from the experimental and control groups, respectively) were included in the analysis

10.1016/j.amsu.2020.11.010 Fogagnolo P, Melardi E, Tranchina L, Rossetti L: Topical citicoline and vitamin B12 versus placebo in the treatment of diabetes-related corneal nerve damage: a randomized double-blind controlled trial

Thats plausible because GLP-1 sensors are found on cells in the intestinal lining and on nearby nerves that relay Im full messages to the brain