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Seek urgent care or emergency help for symptoms such as severe abdominal pain, persistent vomiting or diarrhea, signs of dehydration, trouble breathing or swallowing, swelling of the face, lips, tongue, or throat, fainting, yellowing skin or eyes, or any symptom your clinician has told you to treat as urgent

W.GongG.RyuJ.-S.et al (2012)

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Healthcare providers should engage in shared decision-making with patients, discussing the substantial metabolic benefits of tirzepatide alongside the theoretical thyroid risks, to determine whether the medication is appropriate for each individual's clinical situation and risk profile

When the drug enters the bloodstream, it causes the skin to temporarily darken when exposed to UV light - namely, natural sunlight or sunbeds